Spaglumic acid ( NAAG,N-Acetylaspartylglutamic acid )

产品货号. M22700 CAS No. 3106-85-2

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

Spaglumic acid
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Spaglumic acid is a neuropeptide found in millimolar concentrations in the brain.Spaglumic Acid is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors.
产品描述

Spaglumic acid is a neuropeptide found in millimolar concentrations in the brain.Spaglumic Acid is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. Spaglumic Acid is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes.
同义词

NAAG,N-Acetylaspartylglutamic acid
通路

Proteasome/Ubiquitin
靶点

Endogenous Metabolite
受体

Human Endogenous Metabolite
研究领域

——
适应症

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1.Coyle JT. The nagging question of the function of N-acetylaspartylglutamate. Neurobiol Dis. 1997;4(3-4):231-8.

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