Spaglumic acid

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Spaglumic acid is a neuropeptide found in millimolar concentrations in the brain.Spaglumic Acid is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors.

Spaglumic acid is a neuropeptide found in millimolar concentrations in the brain.Spaglumic Acid is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. Spaglumic Acid is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes.

NAAG,N-Acetylaspartylglutamic acid

Proteasome/Ubiquitin

Endogenous Metabolite

Human Endogenous Metabolite

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3106-85-2

304.26

C11H16N2O8

>98% (HPLC)

Water:29 mg/mL(95.31 mM)

CC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years